Definition:
These excipients are clearly sourced from substances that are explicitly prohibited in Islam—such as gelatin derived from pigs, or materials from animals not slaughtered according to Islamic law, without having undergone the process of istiḥālah (transformative purification).
Why this classification?
All four major Sunni schools of Islamic law—Ḥanafī, Mālikī, Shāfiʿī, and Ḥanbalī—agree that substances derived from ḥarām sources are impermissible for consumption, except in cases of dire necessity (ḍarūrah). This consensus is rooted in clear textual evidences and legal maxims that safeguard purity and ethical sourcing.
Advice:
From Islamic perspective avoid unless there is a clear medical necessity and no suitable alternative is available. In such cases, consult both a qualified medical practitioner and a knowledgeable scholar to determine if an exemption applies.